Laboratory Medicine and Pathobiology
Contact | Courses | Faculty | Overview | Programs: Collaborative, Degree
Faculty Affiliation
Medicine
Degree Programs Offered
Laboratory Medicine and Pathobiology – MSc, PhD
Collaborative Programs
The following collaborative programs are available to students in participating degree programs as listed below:
1. Biomedical Engineering
- Laboratory Medicine and Pathobiology, MSc, PhD
2. Biomedical Toxicology
- Laboratory Medicine and Pathobiology, MSc, PhD
3. Cardiovascular Sciences
- Laboratory Medicine and Pathobiology, MSc, PhD
4. Developmental Biology
- Laboratory Medicine and Pathobiology, PhD
5. Genome Biology and Bioinformatics
- Laboratory Medicine and Pathobiology, PhD
6. Neuroscience
- Laboratory Medicine and Pathobiology, MSc, PhD
The graduate program in Laboratory Medicine and Pathobiology provides a curriculum of courses and a broad-based multidisciplinary approach to research in mechanisms of human disease leading to Master of Science and Doctor of Philosophy degrees. The program emphasizes:
1. Bone and Matrix Pathobiology
2. Cancer
3. Vascular and Cardiovascular Pathobiology
4. Immunopathology, Lymphatics and Transplantation
5. Neuropathobiology and Endocrine Disorders
6. Microbiology and Infectious Disease
Research Foci
Antimicrobial Resistance: Surveillance and Mechanisms
Bone and Connective Tissue Diseases including Disorders of Mineral Metabolism
Cancer Pathogenesis and Prevention
Cardiovascular Disease
Cell-Matrix Interactions
Development: Cell Cycle, Differentiation, Signalling
Diabetes
Endocrine and Neuroendocrine Disorders
Hematopathology and Transfusion Medicine
Immunopathology and Transplantation
Inflammatory Disorders
Lipid Disorders
Lymphatic Pathobiology
Microbial Pathogenesis
Molecular Biomarkers
Neurodegenerative Disorders
Proteomics and Bioinformatics
Protein Structure and Function
Toxicology
Translational Research
Vascular Cell Biology
Viral Diseases
For details consult the departmental Web site www.lmp.facmed.utoronto.ca.
Contact and Address
Admission:
Web: www.lmp.facmed.utoronto.ca
Email: r.ponda@utoronto.ca
Telephone: (416) 978-2550
Fax: (416) 978-7361
Program:
Web: www.lmp.facmed.utoronto.ca
Email: f.dharas@utoronto.ca
Telephone: (416) 978-2663
Fax: (416) 978-7361
Graduate Department of Laboratory Medicine and Pathobiology
Medical Sciences Building
University of Toronto
1 King's College Circle, Room 6243
Toronto, Ontario M5S 1A8
Canada
Degree Programs
Laboratory Medicine and Pathobiology
Master of Science
Minimum Admission Requirements
- Applicants must have completed, or be about to complete, one of the following:
- Pathobiology Specialist Program
- Four-year honours BSc in Life Sciences
- Professional degree (e.g., M.D., D.D.S., D.V.M., or equivalent)
- A minimum A- average over the final two years of undergraduate study.
- Two strong letters of recommendation from faculty members familiar with the applicant's academic work. Departmental appraisal forms must be used.
- Detailed curriculum vitae.
- Statement of intent (approximately 250 words).
- Research experience evidenced by publications, abstracts, or presentations is an asset.
- Successful applicants are selected by the Departmental Admissions Committee on the basis of academic excellence and an interview with a member of the departmental graduate faculty.
- Admission is finalized when a graduate faculty member agrees to supervise the student's research and guarantees a full stipend for the student.
Program Requirements
- Students must be on campus and participating for the duration of their registration in the program.
- Students who have not previously completed LMP 1404H Molecular and Cellular Mechanisms of Disease, or an approved equivalent, will be required to take this course in the first year of their program. Students exempted from LMP 1404H will take a departmental half-course as a substitute. The student's advisory committee may recommend additional courses.
- Students must enrol and participate in a credit/no credit course, LMP 1001Y Graduate Seminars in Laboratory Medicine and Pathobiology, which must be taken throughout the program.
- Students are required to attend the departmental guest lecture series, Seminars in Molecular Pathobiology, that immediately follows the student seminar course LMP1001Y.
- Completion of a thesis under the direction of the student's supervisor, assisted by the advisory committee.
- The duration of the MSc program is usually 18 months. Within 12 to 18 months of entry, students will be advised by their committee to do one of the following:
- write and orally defend a thesis on research completed,
- transfer to the PhD program, or
- withdraw from the MSc program.
- The research content of the MSc thesis is expected to generate the equivalent of one paper published in a peer-reviewed scientific journal.
Doctor of Philosophy
Minimum Admission Requirements
- Two routes of entry are available:
- Track A - Direct entry is available for highly qualified BSc graduates having completed the Pathobiology Specialist Program or a four-year undergraduate program in the life sciences with a minimum A average in the third and fourth years and relevant research experience. These students are encouraged to apply directly to the PhD program.
- Track B - MSc graduates and applicants with a MD, DDS, DVM (or equivalent) degree are eligible for the PhD program. An A- average or higher is required in graduate courses or in a four-year BSc program if there were no course requirements in the MSc program.
- Research experience evidenced by peer-reviewed publications, abstracts, or presentations is normally required.
- Three strong letters of recommendation from faculty members familiar with the applicant's academic work. Departmental appraisal forms must be used. Normally, one of the referees should be the applicant's research supervisor.
- A detailed curriculum vitae.
- Statement of intent (approximately 250 words).
- Applicants are selected by the Departmental Admissions Committee on the basis of academic excellence and successful performance at an interview with a member of the departmental graduate faculty. Admission to the program is finalized when a graduate faculty member agrees to supervise the student's research, and guarantees a full stipend for the student.
- Excellent students with high academic standing (normally minimum A- average on MSc courses) who have clearly demonstrated the ability to do research at the doctoral level may be considered for transfer to the PhD program. Recommendation of the advisory committee is required. Transfer to the PhD program is based on the student's performance at an assessment examination, which is held 12 to 18 months after the start of the MSc program. The student’s supervisor will schedule the assessment examination. The examining committee consists of at least six members of the graduate faculty:
- the Graduate Coordinator (or a representative from the graduate faculty of the Department) who chairs the examination committee,
- the student’s advisory committee, and
- two other graduate faculty members, one of whom is a member from another graduate department.
- A limited number of selected students may enter the MD/PhD program subject to admission into both the departmental PhD program and the MD program.
Program Requirements
- Students must be on campus and participating for the duration of their registration in the program.
- MSc graduates normally complete their PhD programs within four years of registration in the program. Direct entry students and PhD transfer students are expected to complete their PhD programs within five years.
- Students who have not previously completed LMP 1404H Molecular and Cellular Mechanisms of Disease, or an approved equivalent, are required to take this course in the first year of their PhD program. The student's advisory committee may recommend additional courses. Students exempted from LMP 1404H take a departmental half-course as a substitute.
- All students are required to take three half-course equivalents plus an ongoing credit/no credit seminar course, LMP 1001Y. These courses must include at least one half-course in Laboratory Medicine and Pathobiology. Students having completed the undergraduate Pathobiology Specialist Program (or equivalent) are required to take two half-courses in addition to the departmental core course (LMP 1404H) and seminar course (LMP 1001Y). Course work should be completed in the first two years of the program, the continuing seminar course excepted. The latter half of the program is focused on research.
- Students who take additional graduate courses during the MSc program at the University of Toronto and who continue their graduate studies in the PhD program may receive a transfer credit for MSc courses toward doctoral course requirements. Credit for courses from universities other than the University of Toronto must be approved by the Graduate Coordinator; certain restrictions may apply.
- Students are required to attend the departmental guest lecture series, Seminars in Molecular Pathobiology, that immediately follows the student seminar course LMP 1001Y.
- PhD students are normally expected to present at least one graduate research seminar in LMP 1001Y prior to defending their thesis.
- Prior to the start of the third year of the PhD program, the advisory committee may recommend that a PhD student transfer to the MSc program; the student may also request the transfer.
- The PhD thesis is completed under the direction of the candidate's supervisor, assisted by the advisory committee. The candidate normally defends the thesis before a departmental committee, and subsequently before a committee approved by the School of Graduate Studies. Candidates may, with the recommendation of their advisory committee, request a waiver of the Departmental defence, subject to approval by the Graduate Coordinator.
- The PhD thesis must demonstrate a substantial contribution to laboratory medicine and pathobiology, involving a systematic investigation of disease-related hypotheses. The emphasis is on quality of the science and its presentation. The PhD thesis is normally expected to yield the equivalent of three publications in refereed scientific journals.
Course List
Not all courses are offered every year. Please check the departmental Web site, www.lmp.facmed.utoronto.ca, for course availability.
LMP 1001Y Graduate Seminars in Laboratory Medicine and Pathobiology (Credit/No Credit) (Mandatory for all MSc and PhD students in the Department of Laboratory Medicine and Pathobiology)
LMP 1005Y General and Special Pathology (For Oral Pathology Residents only)
LMP 1006H Biological Electron Microscopy
LMP 1012H Seminars on Pathology(Open to students in Biomedical Communications only)
LMP 1013H Neoplasia
LMP 1015H Vascular Pathobiology
LMP 1016H The Pathology of Connective Tissue
LMP 1018H Molecular Biology and Applications to Human Disease
LMP 1019H Research Techniques in Molecular Biology and Pathobiology
LMP 1020H Inflammation, Immunity, and Immunopathology
LMP 1401Y Clinical Biochemistry (For Residents and Diploma students only)
LMP 1404H Molecular and Cellular Mechanisms of Disease (Mandatory for all MSc and PhD students in the Department of Laboratory Medicine and Pathobiology)
LMP 1407H Introductory Clinical Epidemiology and Applied Biostatistics
LMP 1503H Signal Transduction Pathways in Normal and Diseased Tissues
LMP 1504H Cell and Molecular Biology of Cardiovascular Diseases
LMP 1505H Analytical Clinical Biochemistry
LMP 1510H Molecular Biological Aspects of Analytical Biochemistry: Molecular Biology Techniques
LMP 1515H Cell Death Pathways in Development, Tissue Homeostasis and Pathobiology
LMP 1520H Translational Research in Pathobiology
LMP 2115H Selected Topics in Medical Microbiology
RST 9999Y Research Project
Graduate Faculty
Full Members
Abdelhaleem, Mohamed - MSc, PhD
Adeli, Khosrow - DIPCHEM, MSc, PhD
Alman, Benjamin - BSc, MD
Andrulis, Irene - BA, PhD
Asa, Sylvia - MD
Aubert, Isabelle - BSc, PhD
Baines, Andrew - MD, PhD
Bapat, Bharati - BSc, MSc, PhD
Barber, Dwayne - BSc, PhD
Bast, Darrin - BSc, PhD
Bendeck, Michelle - BSc, PhD
Bergeron, Catherine - MD
Boggs, Joan - MSc, PhD
Bognar, Andrew - BSc, PhD
Bremner, Roderick Angus - PhD
Brown, Martha - BSc, MSc, PhD
Brunton, James - BSc, MD
Cole, David - BSc, MD, PhD
Connelly, Philip - BA, PhD
Courtman, David - BSc, MSc, PhD
Cutz, Ernest - MD
Cybulsky, Myron - MD
De Azavedo, Joyce - BSc, PhD
Dennis, James - PhD
Denomme, Gregory - BSc, PhD
Diamandis, Eleftherios - BSc, MD, PhD
Dirks, Peter - MD, PhD
Dittakavi, Sarma - BSc, MSc, PhD
Done, Susan - BA, MA, MBA, BCH, MB, PhD
Drucker, Daniel - MD
Ellen, Richard - DDS
Elsholtz, Harry - BSc, MSc, PhD (Coordinator of Graduate Studies)
Gallinger, Steven - MSc, MD
Girardin, Stephen - BSc, PhD
Gotlieb, Avrum - BSc, MDCM
Grynpas, Marc - MSc, PhD
Gupta, Neeru - BM
Guttman, David - BS, PhD
Hamel, Paul - BSc, PhD
Harrison, Rene - BS, MS, PhD
Hawkins, Cynthia - MD, PhD
Hedley, David - MD
Hegele, Richard - MD (Chair and Graduate Chair)
Hinek, Aleksander - MD, PhD
Hough, Margaret - BSc, PhD
Hu, Jim - BSc, PhD
Husain, Mansoor - MB, MD
Irwin, David - BSc, PhD
Jin, Tianru - PhD
Johnston, Miles - BSc, PhD
Joshi-Sukhwal, Sadhna - BSc, MSc, PhD, DSc
Jothy, Serge - MSc, MD, PhD
Kain, Kevin - MD
Kamel-Reid, Suzanne - BA, MA, PhD
Kandel, Rita - MD
Keeley, Frederick - BSc, PhD
Khokha, Rama - BSc, MSc, PhD
Lazarus, Alan - PhD
Levy, Gary - BSc, MD
Lingwood, Clifford - BSc, PhD
Low, Donald - BSc, MD
Lukacs, Gergely - MD, PhD
Mahuran, Don - BA, PhD
Marsden, Philip - MD
Mazzulli, Tony - MD
McGavin, Martin - BSc, PhD
McKerlie, Colin - DVSM, DVM
McLaurin, Joanne - BSc, MSc, PhD
Minta, Joe - BSc, MBA, MSc, PhD
Mogridge, Jeremy - BSc, PhD
Nag, Sukriti - MSc, MBBS, MD, PhD
Ni, Heyu - MSc, MD, PhD
Ohh, Michael - BSc, PhD
Opas, Michal - MSc, PhD
Ostrowski, Mario - MD
Ozcelik, Hilmi - BSc, MSc, PhD
Palaniyar, Nades - MSc, PhD
Post, Martin - PhD
Pritzker, Kenneth - BSc, MD
Prud'homme, Gerald - MD
Rand, Margaret - BSc, PhD
Reis, Marciano - MD
Robertson, Janice - BSc, PhD
Rosenblum, Norman - MD
Rowe-Magnus, Dean - BSc, MSc, PhD
Rozakis-Adcock, Maria - BSc, PhD
Rutka, James - BSc, LMCC, MD, PhD
Semple, John Wesley - PhD
Seth, Arun - MS, PhD
Shaw, Patricia - SB, MD
Shek, Pang - BSc, MSc, PhD
Sherman, Philip - MD
Squire, Jeremy - BSc, MSc, PhD
Srinivasan, Rajalakshmi - BSc, MA, PhD
Stewart, Duncan - MDCH
Strauss, Bradley - MD
Taylor, Michael - BSc, DRMED, PhD
Tellier, Raymond - BSc, MSc, MSc, MD
Templeton, Douglas - BSc, MD, PhD
Tenenbaum, Howard - DDS, PhD
Thorner, Paul - MD, DPhil
Tsao, Ming-Sound - BSc, MD
van der Kwast, Theodorus - MD, PhD
Vieth, Reinhold - BSc, MSc, PhD
Wang, Chen - MD, PhD
Ward, Michael - MD
Wilson, Gregory - MSc, MD
Wong, Pui-Yuen - BSc, PhD
Yang, Burton - BSc, MSc, PhD
Yeger, Herman - BSc, MScPhm, PhD
Yousef, George - MSc, MD, PhD
Yucel, Yeni - MD
Zacksenhaus, Eldad - PhD
Zhang, Li - MSc, MD, PhD
Zielenska, Maria - MSc, PhD
Members Emeriti
Marks, Alexander - MD, PhD
Moscarello, Mario - BA, MD, PhD
Associate Members
Chang, Hong - MSc, MD, PhD
Crandall, Ian - BSc, MSc, PhD
Crowcroft, Natasha - BA, MA, MSc, MBBS, PhD
Drews, Steven - BA, BSc, MSc, PhD
Fernandes, Bernard - MBChB
Guyard, Cyril - MSc, PhD
Hwang, David - BSc, MD, PhD
Keating, Sarah - MSc, MD
Kingdom, John - DCH, MB, MD
Leytin, Valery - MSc, PhD, DSc
Li, Ren-Ke - MHSc, MSc, MD, PhD
Melano, Roberto - MSc, PhD
Ng, Dominic - MD
Pillai, Dylan - BSc, MD, PhD
Pollanen, Michael - BSc, MD, PhD
Riddell, Robert - LMCC, LRCP, MBBS
Romaschin, Alexander - DIPCHEM, BSc, PhD
Schmitt-Ulms, Gerold - BSc, MSc, DRRERNAT
Somers, Gino - MBBS, BMEDSC, PhD
Tein, Ingrid - MD
Teshima, Ikuko Eileen - PhD